As our beloved dogs age, they can face a range of health challenges that require special attention. Senior dog supplements play a crucial role in maintaining their vitality, supporting their joints, and promoting overall well-being. Whether your dog is entering their golden years or already enjoying retirement, the right supplements can help ensure they stay active, comfortable, and healthy. In this guide, we’ll explore the best senior dog supplements for 2025, offering insights into the top choices for joint health, cognitive function, immune support,

Why Are Senior Dog Supplements Important?
As dogs age, their bodies undergo changes that can affect their health, mobility, and overall quality of life. Senior dog supplements are designed to address these changes, providing essential nutrients that may no longer be as easily absorbed from their regular diet. Supplements can support a range of issues, from joint pain and stiffness to cognitive decline, and help keep your
Key Benefits of Senior Dog Supplements:
- Joint Health: Supplements like glucosamine and chondroitin help maintain healthy joints and ease arthritis pain, promoting better mobility.
- Cognitive Function: Supplements with antioxidants and omega-3 fatty acids support brain health, reducing cognitive decline.
- Immune Support: Senior dogs need additional immune support to stay healthy, especially as they age.
- Digestive Health: Probiotics and fiber supplements can aid digestion and prevent gastrointestinal issues that older dogs are prone to.
- Skin and Coat Health: Omega fatty acids and vitamins promote healthy skin and a shiny coat, addressing dryness and thinning hair that often occurs with age.
Top 5 Best Senior Dog Supplements in 2025
We’ve done the research to bring you the best senior dog supplements available in 2025. These products are specifically designed to support aging dogs and provide relief from common age-related issues.
1. Cosequin DS Plus MSM for Dogs
Best for Joint Health
Cosequin DS Plus MSM is a veterinarian-recommended supplement that’s perfect for senior dogs dealing with joint issues. This formula contains glucosamine, chondroitin sulfate, and MSM (methylsulfonylmethane), three powerful ingredients known for promoting joint health and reducing inflammation. It’s ideal for dogs with arthritis or those showing signs of stiffness or reduced mobility.
Key Features:
- Glucosamine and Chondroitin: Support cartilage health and protect joints from wear and tear.
- MSM: Helps reduce inflammation and improve joint function.
- Easy to Administer: Comes in chewable tablets that most dogs love.
- Vet-Approved: Trusted by veterinarians to promote long-term joint health.
Why We Love It:
Cosequin DS Plus MSM is an excellent choice for senior dogs suffering from arthritis or general joint stiffness. The combination of glucosamine, chondroitin, and MSM provides comprehensive support for joint health and mobility, helping your dog stay active.
2. Nutramax Dasuquin with MSM

Nutramax Cosequin Joint Health Supplement with Glucosamine, Chondroitin & MSM Chewable Tablets for Dogs, 60 count
Best for Comprehensive Joint Support
Nutramax Dasuquin with MSM is another fantastic option for senior dogs with joint issues. It’s a top-tier joint supplement formulated with glucosamine, chondroitin, and MSM, as well as ASU (avocado/soybean unsaponifiables), which are known to have additional joint-supporting benefits. It’s an all-in-one solution that provides comprehensive care for aging dogs’ joints.
Key Features:
- Glucosamine and Chondroitin: Proven to help protect and maintain cartilage health.
- MSM and ASU: These ingredients reduce inflammation and support joint function.
- Highly Effective: Clinically proven to help maintain healthy joint function and improve mobility.
- Chewable Tablets: Easy for dogs to consume, ensuring they get the nutrients they need.
Why We Love It:
Nutramax Dasuquin is a highly effective joint supplement that combines multiple powerful ingredients to ensure your dog’s joints are supported throughout their senior years. The addition of ASU makes it a unique choice for those looking for comprehensive joint health support.
3. VetriScience Laboratories GlycoFlex 3

VetriScience GlycoFlex Plus Peanut Butter Flavored Chews Joint Supplement for Medium & Large Dogs, 120 count
Best for Active Senior Dogs
For senior dogs that are still active and love to run around, VetriScience Laboratories GlycoFlex 3 is an excellent supplement. This advanced joint support formula contains glucosamine, MSM, and green-lipped mussel, a natural ingredient known for its anti-inflammatory properties and ability to support joint flexibility and mobility.
Key Features:
- Glucosamine and MSM: Strengthens cartilage and relieves joint discomfort.
- Green-Lipped Mussel: A natural source of omega-3 fatty acids and antioxidants for joint health.
- Advanced Support: Ideal for active senior dogs who need extra joint protection.
- Soft Chews: Easy to administer, making it ideal for dogs with dietary restrictions or picky eaters.
Why We Love It:
GlycoFlex 3 is specifically designed for senior dogs that still enjoy physical activity. The combination of glucosamine, MSM, and green-lipped mussel ensures your dog has the support they need for active joints, promoting flexibility and comfort.
4. ProSense Senior Dog Multivitamin
Best for Overall Health Support
ProSense Senior Dog Multivitamin is a comprehensive multivitamin formulated for senior dogs. It provides a wide range of essential vitamins, minerals, and antioxidants to support your dog’s overall health, including heart, immune, and skin health. It’s an excellent choice if you’re looking to give your senior dog a daily boost of nutrients.
Key Features:
- Complete Vitamin and Mineral Formula: Supports overall health and vitality in senior dogs.
- Antioxidants: Helps fight free radicals, promoting a strong immune system and better skin health.
- Easy to Administer: Comes in chewable tablets that your dog will enjoy.
- Affordable: An excellent, budget-friendly option for supporting your dog’s overall well-being.
Why We Love It:
ProSense Senior Dog Multivitamin is an all-in-one supplement that provides complete support for your dog’s overall health. From heart health to skin and coat maintenance, this supplement covers a broad spectrum of needs for senior dogs.
5. VetriScience Laboratories Cognitive Support
Best for Brain Health and Cognitive Function
As dogs age, they may experience cognitive dysfunction, which can lead to confusion, memory loss, and changes in behavior. VetriScience Laboratories Cognitive Support is designed to support brain health and cognitive function in senior dogs. It contains antioxidants, B vitamins, and phosphatidylserine to promote healthy brain aging.
Key Features:
- Antioxidants: Helps protect brain cells from oxidative damage.
- B Vitamins and Phosphatidylserine: Support healthy brain function and memory.
- Promotes Mental Sharpness: Helps reduce the signs of cognitive dysfunction.
- Soft Chews: Easy to administer and tasty for your dog.
Why We Love It:
VetriScience Cognitive Support is a great supplement for dogs showing signs of cognitive decline. The combination of antioxidants and brain-supporting ingredients helps improve memory, focus, and mental clarity, ensuring your senior dog stays sharp as they age.
How to Choose the Best Senior Dog Supplements
When selecting supplements for your senior dog, consider the following factors:
- Health Concerns: If your dog is suffering from joint pain, look for a joint supplement. For cognitive health, opt for a brain support supplement.
- Ingredients: Always check the ingredients list for high-quality nutrients that are beneficial for your dog’s specific needs.
- Vet Approval: Look for supplements that are veterinarian-approved or recommended to ensure they are safe and effective.
- Administration: Choose supplements that are easy to administer, whether in tablet or chew form, to ensure your dog gets the proper dosage.
Final Thoughts
Senior dog supplements play a vital role in helping your dog live their golden years with comfort and vitality. From joint support to cognitive health, the best supplements can significantly improve your dog’s quality of life in their later years. Products like Cosequin DS Plus MSM, Nutramax Dasuquin, and VetriScience GlycoFlex 3 continue to be top choices for providing comprehensive support for aging dogs. By selecting the right supplements and working with your vet, you can ensure your senior dog remains active, happy, and healthy.